IDIOT

Aminoglycosides that are derived from bacteria of the Streptomyces genus are named with the suffix -mycin, while those which are derived from Micromonospora are named with the suffix -micin.

Aminoglycosides are used for serious gram-negative infections, especially Pseudomonas aeruginosa. They are active against most gram-negative aerobic bacilli but lack activity against anaerobes and most gram-positive bacteria, except for most staphylococci. It Inhibit protein synthesis by binding to a portion of the bacterial ribosome. Most of them are bacteriocidal.

They are not absorbed from the intestine, they are usually given by injection. Aminoglycosides are quite toxic, with side effects including damage to the ears and kidneys. For this reason they are only used for infections that do not respond to other antibiotics.